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HCRP-1 regulates EGFR–AKT–BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer
Hepatocellular carcinoma-related protein-1 (HCRP-1), a subunit of mammalian endosomal sorting complex required for transport-I (ESCRT-I), is frequently downregulated in various kinds of malignant tumors. The role of HCRP-1 in colorectal cancer (CRC) remains unknown. We investigate the clinical value...
Autores principales: | Chen, Feifei, Zhang, Lei, Wu, Jianqiang, Huo, Fuchun, Ren, Xin, Zheng, Junnian, Pei, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281589/ https://www.ncbi.nlm.nih.gov/pubmed/30518879 http://dx.doi.org/10.1038/s41419-018-1217-2 |
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