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UBIAD1 suppresses the proliferation of bladder carcinoma cells by regulating H-Ras intracellular trafficking via interaction with the C-terminal domain of H-Ras

UbiA prenyltransferase domain-containing protein 1 (UBIAD1) plays a key role in biosynthesis of vitamin K(2) and coenzyme Q10 using geranylgeranyl diphosphate (GGPP). However, the mechanism by which UBIAD1 participates in tumorigenesis remains unknown. This study show that UBIAD1 interacts with H-Ra...

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Detalles Bibliográficos
Autores principales: Xu, Zhiliang, Duan, Fengsen, Lu, Huiai, Abdulkadhim Dragh, Maytham, Xia, Yanzhi, Liang, Huageng, Hong, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281600/
https://www.ncbi.nlm.nih.gov/pubmed/30518913
http://dx.doi.org/10.1038/s41419-018-1215-4

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