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Identification of potential genetic risk factors for bipolar disorder by whole-exome sequencing

This study aims at assessing the burden of rare (minor allele frequency < 1%) predicted damaging variants in the whole exome of 92 bipolar I disorder (BD) patients and 1051 controls of French ancestry. Patients exhibiting an extreme phenotype (earlier onset and family history of mood disorder) we...

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Detalles Bibliográficos
Autores principales:	Husson, Thomas, Duboc, Jean-Baptiste, Quenez, Olivier, Charbonnier, Camille, Rotharmel, Maud, Cuenca, Macarena, Jegouzo, Xavier, Richard, Anne-Claire, Frebourg, Thierry, Deleuze, Jean-François, Boland, Anne, Genin, Emmanuelle, Debette, Stéphanie, Tzourio, Christophe, Campion, Dominique, Nicolas, Gaël, Guillin, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281607/ https://www.ncbi.nlm.nih.gov/pubmed/30518751 http://dx.doi.org/10.1038/s41398-018-0291-7

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