Nutritional stress reprograms dedifferention in glioblastoma multiforme driven by PTEN/Wnt/Hedgehog axis: a stochastic model of cancer stem cells

The emergence and maintenance of cancer stem-like cells (CSCs) are usually governed by tumor niche. Tumor niche always provides metabolic challenges to cancer cells and CSCs mostly because of tissue hypoxia. However, the role of micro-environmental nutritional stress (NS) in dedifferentiation of can...

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Detalles Bibliográficos
Autores principales: Mondal, Susmita, Bhattacharya, Kaushik, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281623/
https://www.ncbi.nlm.nih.gov/pubmed/30534418
http://dx.doi.org/10.1038/s41420-018-0126-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281623/
https://www.ncbi.nlm.nih.gov/pubmed/30534418
http://dx.doi.org/10.1038/s41420-018-0126-6

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