Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice

The pace of repair declines with age and, while exposure to a young circulation can rejuvenate fracture repair, the cell types and factors responsible for rejuvenation are unknown. Here we report that young macrophage cells produce factors that promote osteoblast differentiation of old bone marrow s...

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Detalles Bibliográficos
Autores principales: Vi, Linda, Baht, Gurpreet S., Soderblom, Erik J., Whetstone, Heather, Wei, Qingxia, Furman, Bridgette, Puviindran, Vijitha, Nadesan, Puviindran, Foster, Matthew, Poon, Raymond, White, James P., Yahara, Yasuhito, Ng, Adeline, Barrientos, Tomasa, Grynpas, Marc, Mosely, M. Arthur, Alman, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281653/
https://www.ncbi.nlm.nih.gov/pubmed/30518764
http://dx.doi.org/10.1038/s41467-018-07666-0

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