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Inactivation of Lon protease reveals a link between mitochondrial unfolded protein stress and mitochondrial translation inhibition

The mitochondrial Unfolded Protein Response (UPR(mt)) pathway confers protection from misfolded and aggregated proteins by activating factors that promote protein folding and degradation. Our recent work on Lon protease, a member of the mitochondrial ATPase Associated with diverse cellular Activitie...

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Detalles Bibliográficos
Autores principales: Pareek, Gautam, Pallanck, Leo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281655/
https://www.ncbi.nlm.nih.gov/pubmed/30518747
http://dx.doi.org/10.1038/s41419-018-1213-6