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The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells
Semaphorin 6A (SEMA6A), a membrane-bound protein, is downregulated in lung cancer tissue compared to its adjacent normal tissue. However, the functions of SEMA6A in lung cancer cells are still unclear. In the present study, full length SEMA6A and various truncations were transfected into lung cancer...
Autores principales: | Shen, Cheng-Ying, Chang, Ya-Chu, Chen, Li-Han, Lin, Wen-Chun, Lee, Yung-Hua, Yeh, Shu-Tsen, Chen, Hsin-Kuang, Fang, Wentao, Hsu, Chung-Ping, Lee, Jang-Ming, Lu, Tzu-Pin, Hsiao, Pei-Wen, Lai, Liang-Chuan, Tsai, Mong-Hsun, Chuang, Eric Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281666/ https://www.ncbi.nlm.nih.gov/pubmed/30518871 http://dx.doi.org/10.1038/s41389-018-0105-z |
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