BK channel blocker paxilline attenuates thalidomide-caused synaptic and cognitive dysfunctions in mice

Thalidomide is a widely prescribed immunomodulatory drug (iMiD) for multiple myeloma, but causes reversible memory loss in humans. However, how thalidomide causes cognitive dysfunction at a cellular and molecular level has not been demonstrated. We studied the effect of thalidomide on synaptic funct...

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Detalles Bibliográficos
Autores principales: Choi, Tae-Yong, Lee, Seung-Hyun, Kim, Soo-Jeong, Jo, Youhwa, Park, Chul-Seung, Choi, Se-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281727/
https://www.ncbi.nlm.nih.gov/pubmed/30518785
http://dx.doi.org/10.1038/s41598-018-36367-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281727/
https://www.ncbi.nlm.nih.gov/pubmed/30518785
http://dx.doi.org/10.1038/s41598-018-36367-3

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