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BK channel blocker paxilline attenuates thalidomide-caused synaptic and cognitive dysfunctions in mice
Thalidomide is a widely prescribed immunomodulatory drug (iMiD) for multiple myeloma, but causes reversible memory loss in humans. However, how thalidomide causes cognitive dysfunction at a cellular and molecular level has not been demonstrated. We studied the effect of thalidomide on synaptic funct...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281727/ https://www.ncbi.nlm.nih.gov/pubmed/30518785 http://dx.doi.org/10.1038/s41598-018-36367-3 |