Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations

Effector and memory CD8 T cells have an intrinsic difference in the way they must approach antigen; effector cells need to address the pathogen at hand and therefore favor outgrowth of only high-affinity clones. In contrast, the memory pool benefits from greater clonal diversity to recognize and eli...

Descripción completa

Detalles Bibliográficos
Autores principales: Kavazović, Inga, Polić, Bojan, Wensveen, Felix M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281969/
https://www.ncbi.nlm.nih.gov/pubmed/30555492
http://dx.doi.org/10.3389/fimmu.2018.02831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281969/
https://www.ncbi.nlm.nih.gov/pubmed/30555492
http://dx.doi.org/10.3389/fimmu.2018.02831

Ejemplares similares