Enzymatic Activity Is Not Required for Phospholipase D Mediated TNF-α Regulation and Myocardial Healing

Phospholipase D1 is a regulator of tumor necrosis factor-α expression and release upon LPS-induced sepsis and following myocardial infarction (MI). Lack of PLD1 leads to a reduced TNF-α mediated inflammatory response and to enhanced infarct size with declined cardiac function 21 days after ischemia...

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Detalles Bibliográficos
Autores principales: Klier, Meike, Gorressen, Simone, Urbahn, Marc-Andre, Barbosa, David, Ouwens, Margriet, Fischer, Jens W., Elvers, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281985/
https://www.ncbi.nlm.nih.gov/pubmed/30555342
http://dx.doi.org/10.3389/fphys.2018.01698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281985/
https://www.ncbi.nlm.nih.gov/pubmed/30555342
http://dx.doi.org/10.3389/fphys.2018.01698

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