Sequential Prodrug Strategy To Target and Eliminate ACPA-Selective Autoreactive B Cells

[Image: see text] Autoreactive B cells are thought to play a pivotal role in many autoimmune diseases. Rheumatoid arthritis (RA) is an autoimmune disease affecting ∼1% of the Western population and is hallmarked by the presence of anticitrullinated proteins antibodies (ACPA) produced by autoreactive...

Descripción completa

Detalles Bibliográficos
Autores principales: Lelieveldt, Lianne P. W. M., Kristyanto, Hendy, Pruijn, Ger J. M., Scherer, Hans Ulrich, Toes, René E. M., Bonger, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282105/
https://www.ncbi.nlm.nih.gov/pubmed/30289723
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282105/
https://www.ncbi.nlm.nih.gov/pubmed/30289723
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00741

Ejemplares similares