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Buffering and Amplifying Transcriptional Noise During Cell Fate Specification

The molecular processes that drive gene transcription are inherently noisy. This noise often manifests in the form of transcriptional bursts, producing fluctuations in gene activity over time. During cell fate specification, this noise is often buffered to ensure reproducible developmental outcomes....

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Detalles Bibliográficos
Autores principales: Urban, Elizabeth A., Johnston, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282114/
https://www.ncbi.nlm.nih.gov/pubmed/30555516
http://dx.doi.org/10.3389/fgene.2018.00591