Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells

The present data describe the relative neuro-2a cellular differentiation induced by reducing serum concentration (0.1% FBS) in DMEM in the presence/absence of 20 μM retinoic acid (RA). Neurite outgrowth was observed within 24 h in DMEM supplemented with reduced serum and retinoic acid (GpIV). The CF...

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Detalles Bibliográficos
Autores principales: Kumar, Mukesh, Katyal, Anju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282191/
https://www.ncbi.nlm.nih.gov/pubmed/30547071
http://dx.doi.org/10.1016/j.dib.2018.11.097
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author Kumar, Mukesh
Katyal, Anju
author_facet Kumar, Mukesh
Katyal, Anju
author_sort Kumar, Mukesh
collection PubMed
description The present data describe the relative neuro-2a cellular differentiation induced by reducing serum concentration (0.1% FBS) in DMEM in the presence/absence of 20 μM retinoic acid (RA). Neurite outgrowth was observed within 24 h in DMEM supplemented with reduced serum and retinoic acid (GpIV). The CFSE based proliferation assay data signified cessation of neuro-2a cellular proliferation in GpIV. An increase in the number of cells arrested at G(0)/G(1) phase was also evident in GpIV and DMEM supplemented with 0.1% FBS (GpIII). Moreover, GpIV cells had improved mRNA and protein expression of Rbfox3/NeuN and choline acetyltransferase (ChAT).
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spelling pubmed-62821912018-12-13 Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells Kumar, Mukesh Katyal, Anju Data Brief Neuroscience The present data describe the relative neuro-2a cellular differentiation induced by reducing serum concentration (0.1% FBS) in DMEM in the presence/absence of 20 μM retinoic acid (RA). Neurite outgrowth was observed within 24 h in DMEM supplemented with reduced serum and retinoic acid (GpIV). The CFSE based proliferation assay data signified cessation of neuro-2a cellular proliferation in GpIV. An increase in the number of cells arrested at G(0)/G(1) phase was also evident in GpIV and DMEM supplemented with 0.1% FBS (GpIII). Moreover, GpIV cells had improved mRNA and protein expression of Rbfox3/NeuN and choline acetyltransferase (ChAT). Elsevier 2018-11-23 /pmc/articles/PMC6282191/ /pubmed/30547071 http://dx.doi.org/10.1016/j.dib.2018.11.097 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Neuroscience
Kumar, Mukesh
Katyal, Anju
Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title_full Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title_fullStr Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title_full_unstemmed Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title_short Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells
title_sort data on retinoic acid and reduced serum concentration induced differentiation of neuro-2a neuroblastoma cells
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282191/
https://www.ncbi.nlm.nih.gov/pubmed/30547071
http://dx.doi.org/10.1016/j.dib.2018.11.097
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