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Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response
Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome. In the case of Mycobacterium tuberculosis, the bacterium perforates the phag...
Autores principales: | Mittal, Ekansh, Skowyra, Michael L., Uwase, Grace, Tinaztepe, Emir, Mehra, Alka, Köster, Stefan, Hanson, Phyllis I., Philips, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282207/ https://www.ncbi.nlm.nih.gov/pubmed/30482832 http://dx.doi.org/10.1128/mBio.01765-18 |
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