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Bridging gaps in transposable element research with single-molecule and single-cell technologies
More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282271/ http://dx.doi.org/10.1186/s13100-018-0140-5 |
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author | Kutter, Claudia Jern, Patric Suh, Alexander |
author_facet | Kutter, Claudia Jern, Patric Suh, Alexander |
author_sort | Kutter, Claudia |
collection | PubMed |
description | More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2(nd) Uppsala Transposon Symposium on October 4–5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research. |
format | Online Article Text |
id | pubmed-6282271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-62822712018-12-10 Bridging gaps in transposable element research with single-molecule and single-cell technologies Kutter, Claudia Jern, Patric Suh, Alexander Mob DNA Meeting Report More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2(nd) Uppsala Transposon Symposium on October 4–5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research. BioMed Central 2018-12-06 /pmc/articles/PMC6282271/ http://dx.doi.org/10.1186/s13100-018-0140-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Meeting Report Kutter, Claudia Jern, Patric Suh, Alexander Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title_full | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title_fullStr | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title_full_unstemmed | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title_short | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
title_sort | bridging gaps in transposable element research with single-molecule and single-cell technologies |
topic | Meeting Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282271/ http://dx.doi.org/10.1186/s13100-018-0140-5 |
work_keys_str_mv | AT kutterclaudia bridginggapsintransposableelementresearchwithsinglemoleculeandsinglecelltechnologies AT jernpatric bridginggapsintransposableelementresearchwithsinglemoleculeandsinglecelltechnologies AT suhalexander bridginggapsintransposableelementresearchwithsinglemoleculeandsinglecelltechnologies |