A statistical measure for the skewness of X chromosome inactivation based on family trios

BACKGROUND: X chromosome inactivation (XCI) is an important gene regulation mechanism in females to equalize the expression levels of X chromosome between two sexes. Generally, one of two X chromosomes in females is randomly chosen to be inactivated. Nonrandom XCI (XCI skewing) is also observed in f...

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Detalles Bibliográficos
Autores principales: Xu, Si-Qi, Zhang, Yu, Wang, Peng, Liu, Wei, Wu, Xian-Bo, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282303/
https://www.ncbi.nlm.nih.gov/pubmed/30518319
http://dx.doi.org/10.1186/s12863-018-0694-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282303/
https://www.ncbi.nlm.nih.gov/pubmed/30518319
http://dx.doi.org/10.1186/s12863-018-0694-8

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