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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study

BACKGROUND: Aryl hydrocarbon receptor (AhR) ligands may act as potential carcinogens or anti-tumor agents. Understanding how some of the residues in AhR ligand binding domain (AhRLBD) modulate their interactions with ligands would be useful in assessing their divergent roles including toxic and bene...

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Detalles Bibliográficos
Autores principales: Chitrala, Kumaraswamy Naidu, Yang, Xiaoming, Nagarkatti, Prakash, Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282305/
https://www.ncbi.nlm.nih.gov/pubmed/30522477
http://dx.doi.org/10.1186/s12900-018-0095-2