Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

OBJECTIVE: Immune cell adaptor protein SKAP1 couples the antigen-receptor (TCR/CD3) with the activation of LFA-1 adhesion in T-cells. Previous work by ourselves and others have shown that SKAP1 can directly bind to other adaptors such as ADAP and RapL. However, it has been unclear whether SKAP1 can...

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Detalles Bibliográficos
Autores principales: Raab, Monika, Strebhardt, Klaus, Rudd, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282339/
https://www.ncbi.nlm.nih.gov/pubmed/30522503
http://dx.doi.org/10.1186/s13104-018-3976-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282339/
https://www.ncbi.nlm.nih.gov/pubmed/30522503
http://dx.doi.org/10.1186/s13104-018-3976-3

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