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Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region
OBJECTIVE: Immune cell adaptor protein SKAP1 couples the antigen-receptor (TCR/CD3) with the activation of LFA-1 adhesion in T-cells. Previous work by ourselves and others have shown that SKAP1 can directly bind to other adaptors such as ADAP and RapL. However, it has been unclear whether SKAP1 can...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282339/ https://www.ncbi.nlm.nih.gov/pubmed/30522503 http://dx.doi.org/10.1186/s13104-018-3976-3 |