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bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling

BACKGROUND: Human pluripotent stem cells (PSCs) open new windows for basic research and regenerative medicine due to their remarkable properties, i.e. their ability to self-renew indefinitely and being pluripotent. There are different, conflicting data related to the role of basic fibroblast growth...

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Detalles Bibliográficos
Autores principales: Haghighi, Fereshteh, Dahlmann, Julia, Nakhaei-Rad, Saeideh, Lang, Alexander, Kutschka, Ingo, Zenker, Martin, Kensah, George, Piekorz, Roland P., Ahmadian, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282345/
https://www.ncbi.nlm.nih.gov/pubmed/30518391
http://dx.doi.org/10.1186/s12964-018-0307-1