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Isolation and characterization of camelid single-domain antibodies against HER2

OBJECTIVE: To isolate and characterize novel high-affinity llama single-domain antibodies against human HER2. RESULTS: We immunized a llama with human HER2, constructed a phage-displayed V(H)H library from the lymphocytes of the animal, and isolated six unique HER2-specific V(H)Hs by panning. All si...

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Detalles Bibliográficos
Autores principales:	Hussack, Greg, Raphael, Shalini, Lowden, Michael J., Henry, Kevin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282393/ https://www.ncbi.nlm.nih.gov/pubmed/30518413 http://dx.doi.org/10.1186/s13104-018-3955-8

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