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A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators
Clinical observation of condensation at the gas flow exit of blood oxygenators is a recurrent event during cardiopulmonary bypass. These devices consist of a bundle of hollow fibers made of a microporous membrane that allows the exchange of O(2) and CO(2). The fibers carry a gas mixture inside (intr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282549/ https://www.ncbi.nlm.nih.gov/pubmed/30155896 http://dx.doi.org/10.1111/aor.13277 |
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author | Gómez Bardón, Ricardo Dubini, Gabriele Pennati, Giancarlo |
author_facet | Gómez Bardón, Ricardo Dubini, Gabriele Pennati, Giancarlo |
author_sort | Gómez Bardón, Ricardo |
collection | PubMed |
description | Clinical observation of condensation at the gas flow exit of blood oxygenators is a recurrent event during cardiopulmonary bypass. These devices consist of a bundle of hollow fibers made of a microporous membrane that allows the exchange of O(2) and CO(2). The fibers carry a gas mixture inside (intraluminal flow), while blood flows externally around them (extraluminal flow). Although different studies described this effect in the past, the specific role of the different sections of the device requires further analysis, and the total condensation rate remains unquantified. In this study, a closer look is taken at the transition of gas between the oxygenation bundle and the external room air. A method is proposed to estimate the total condensate output, combining computational fluid dynamics (CFD) of thermal distribution and a simplified 1D model of water vapor saturation of gas. The influence of a number of different parameters is analyzed, regarding material properties, environmental conditions, and clinical use. Results show that condensation rate could vary in a 30‐fold range within reasonably small variations of the different variables considered. |
format | Online Article Text |
id | pubmed-6282549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-62825492018-12-11 A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators Gómez Bardón, Ricardo Dubini, Gabriele Pennati, Giancarlo Artif Organs Electronic‐Only Articles Clinical observation of condensation at the gas flow exit of blood oxygenators is a recurrent event during cardiopulmonary bypass. These devices consist of a bundle of hollow fibers made of a microporous membrane that allows the exchange of O(2) and CO(2). The fibers carry a gas mixture inside (intraluminal flow), while blood flows externally around them (extraluminal flow). Although different studies described this effect in the past, the specific role of the different sections of the device requires further analysis, and the total condensation rate remains unquantified. In this study, a closer look is taken at the transition of gas between the oxygenation bundle and the external room air. A method is proposed to estimate the total condensate output, combining computational fluid dynamics (CFD) of thermal distribution and a simplified 1D model of water vapor saturation of gas. The influence of a number of different parameters is analyzed, regarding material properties, environmental conditions, and clinical use. Results show that condensation rate could vary in a 30‐fold range within reasonably small variations of the different variables considered. John Wiley and Sons Inc. 2018-08-29 2018-11 /pmc/articles/PMC6282549/ /pubmed/30155896 http://dx.doi.org/10.1111/aor.13277 Text en © 2018 The Authors. Artificial Organs published by Wiley Periodicals, Inc. on behalf of International Center for Artificial Organ and Transplantation (ICAOT) This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Electronic‐Only Articles Gómez Bardón, Ricardo Dubini, Gabriele Pennati, Giancarlo A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title | A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title_full | A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title_fullStr | A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title_full_unstemmed | A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title_short | A Computational Model of Heat Loss and Water Condensation on the Gas‐Side of Blood Oxygenators |
title_sort | computational model of heat loss and water condensation on the gas‐side of blood oxygenators |
topic | Electronic‐Only Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282549/ https://www.ncbi.nlm.nih.gov/pubmed/30155896 http://dx.doi.org/10.1111/aor.13277 |
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