Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells

Type I and type III interferons (IFNs) are fundamental for antiviral immunity, but prolonged expression is also detrimental to the host. Therefore, upon viral infection high levels of type I and III IFNs are followed by a strong and rapid decline. However, the mechanisms responsible for this suppres...

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Detalles Bibliográficos
Autores principales: Newling, Melissa, Hoepel, Willianne, Vogelpoel, Lisa T.C., Heineke, Marieke H., van Burgsteden, Johan A., Taanman‐Kueter, Esther W.M., Eggink, Dirk, Kuijpers, Taco W., Beaumont, Tim, van Egmond, Marjolein, Kapsenberg, Martien L., Baeten, Dominique L.P., den Dunnen, Jeroen, de Jong, Esther C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Innate immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282563/
https://www.ncbi.nlm.nih.gov/pubmed/30184252
http://dx.doi.org/10.1002/eji.201847615

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