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Pharmacokinetics, Excretion, and Mass Balance of [(14)C]‐Batefenterol Following a Single Microtracer Intravenous Dose (Concomitant to an Inhaled Dose) or Oral Dose of Batefenterol in Healthy Men

Inhaled batefenterol is an investigational bifunctional molecule for the treatment of chronic obstructive pulmonary disease. The excretion balance and pharmacokinetics of batefenterol using [(14)C]‐radiolabeled drug administered orally and as intravenous (IV) infusion were assessed. In this 2‐period...

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Detalles Bibliográficos
Autores principales: Ambery, Claire, Young, Graeme, Fuller, Teresa, Lazaar, Aili L., Pereira, Adrian, Hughes, Adam, Ramsay, David, van den Berg, Frans, Daley‐Yates, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282586/
https://www.ncbi.nlm.nih.gov/pubmed/30230263
http://dx.doi.org/10.1002/cpdd.616