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Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression

The data set presented here is associated with the article “Intracellular calcium and NF-(k)B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated wit...

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Detalles Bibliográficos
Autores principales: Al-Anazi, Azizah, Parhar, Ranjit, Saleh, Soad, Al-Hijailan, Reem, Inglis, Angela, Al-Jufan, Mansour, Bazzi, Mohammed, Hashmi, Sarwar, Conca, Walter, Collison, Kate, Al-Mohanna, Futwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282628/
https://www.ncbi.nlm.nih.gov/pubmed/30547064
http://dx.doi.org/10.1016/j.dib.2018.10.147
Descripción
Sumario:The data set presented here is associated with the article “Intracellular calcium and NF-(k)B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5–1.5% oxygen in the presence and absence of BAPTA-AM or the NF-κB inhibitor SN50 for 48 h prior to RNA isolation and PCR analysis.