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Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression
The data set presented here is associated with the article “Intracellular calcium and NF-(k)B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated wit...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282628/ https://www.ncbi.nlm.nih.gov/pubmed/30547064 http://dx.doi.org/10.1016/j.dib.2018.10.147 |
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author | Al-Anazi, Azizah Parhar, Ranjit Saleh, Soad Al-Hijailan, Reem Inglis, Angela Al-Jufan, Mansour Bazzi, Mohammed Hashmi, Sarwar Conca, Walter Collison, Kate Al-Mohanna, Futwan |
author_facet | Al-Anazi, Azizah Parhar, Ranjit Saleh, Soad Al-Hijailan, Reem Inglis, Angela Al-Jufan, Mansour Bazzi, Mohammed Hashmi, Sarwar Conca, Walter Collison, Kate Al-Mohanna, Futwan |
author_sort | Al-Anazi, Azizah |
collection | PubMed |
description | The data set presented here is associated with the article “Intracellular calcium and NF-(k)B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5–1.5% oxygen in the presence and absence of BAPTA-AM or the NF-κB inhibitor SN50 for 48 h prior to RNA isolation and PCR analysis. |
format | Online Article Text |
id | pubmed-6282628 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-62826282018-12-13 Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression Al-Anazi, Azizah Parhar, Ranjit Saleh, Soad Al-Hijailan, Reem Inglis, Angela Al-Jufan, Mansour Bazzi, Mohammed Hashmi, Sarwar Conca, Walter Collison, Kate Al-Mohanna, Futwan Data Brief Biochemistry, Genetics and Molecular Biology The data set presented here is associated with the article “Intracellular calcium and NF-(k)B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5–1.5% oxygen in the presence and absence of BAPTA-AM or the NF-κB inhibitor SN50 for 48 h prior to RNA isolation and PCR analysis. Elsevier 2018-11-01 /pmc/articles/PMC6282628/ /pubmed/30547064 http://dx.doi.org/10.1016/j.dib.2018.10.147 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Biochemistry, Genetics and Molecular Biology Al-Anazi, Azizah Parhar, Ranjit Saleh, Soad Al-Hijailan, Reem Inglis, Angela Al-Jufan, Mansour Bazzi, Mohammed Hashmi, Sarwar Conca, Walter Collison, Kate Al-Mohanna, Futwan Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title | Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title_full | Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title_fullStr | Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title_full_unstemmed | Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title_short | Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
title_sort | data on hypoxia-induced vegf, leptin and nf-kb p65 expression |
topic | Biochemistry, Genetics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282628/ https://www.ncbi.nlm.nih.gov/pubmed/30547064 http://dx.doi.org/10.1016/j.dib.2018.10.147 |
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