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Avenues to Characterize the Interactions of Extended N‐Glycans with Proteins by NMR Spectroscopy: The Influenza Hemagglutinin Case

Long‐chain multiantenna N‐glycans are extremely complex molecules. Their inherent flexibility and the presence of repetitions of monosaccharide units in similar chemical environments hamper their full characterization by X‐ray diffraction or standard NMR methods. Herein, the successful conformationa...

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Detalles Bibliográficos
Autores principales: Fernández de Toro, Beatriz, Peng, Wenjie, Thompson, Andrew J., Domínguez, Gema, Cañada, F. Javier, Pérez‐Castells, Javier, Paulson, James C., Jiménez‐Barbero, Jesús, Canales, Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282704/
https://www.ncbi.nlm.nih.gov/pubmed/30238596
http://dx.doi.org/10.1002/anie.201807162