Synergistic cross‐talk of hedgehog and interleukin‐6 signaling drives growth of basal cell carcinoma

Persistent activation of hedgehog (HH)/GLI signaling accounts for the development of basal cell carcinoma (BCC), a very frequent nonmelanoma skin cancer with rising incidence. Targeting HH/GLI signaling by approved pathway inhibitors can provide significant therapeutic benefit to BCC patients. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales: Sternberg, Christina, Gruber, Wolfgang, Eberl, Markus, Tesanovic, Suzana, Stadler, Manuela, Elmer, Dominik P., Schlederer, Michaela, Grund, Sandra, Roos, Simone, Wolff, Florian, Kaur, Supreet, Mangelberger, Doris, Lehrach, Hans, Hache, Hendrik, Wierling, Christoph, Laimer, Josef, Lackner, Peter, Wiederstein, Markus, Kasper, Maria, Risch, Angela, Petzelbauer, Peter, Moriggl, Richard, Kenner, Lukas, Aberger, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Molecular Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282712/
https://www.ncbi.nlm.nih.gov/pubmed/29987839
http://dx.doi.org/10.1002/ijc.31724

Ejemplares similares

Ejemplares similares