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Epithelial‐to‐mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

The process of epithelial‐to‐mesenchymal transition (EMT) in cancer is a well‐described process whereby epithelial tumour cells undergo molecular/phenotypic changes and transition to a mesenchymal biology. To aid in the transcriptional characterisation of this process, gene expression signatures hav...

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Detalles Bibliográficos
Autores principales: McCorry, Amy MB, Loughrey, Maurice B, Longley, Daniel B, Lawler, Mark, Dunne, Philip D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282832/
https://www.ncbi.nlm.nih.gov/pubmed/30105762
http://dx.doi.org/10.1002/path.5155