Cargando…
Design and estimation in clinical trials with subpopulation selection
Population heterogeneity is frequently observed among patients' treatment responses in clinical trials because of various factors such as clinical background, environmental, and genetic factors. Different subpopulations defined by those baseline factors can lead to differences in the benefit or...
Autores principales: | Chiu, Yi‐Da, Koenig, Franz, Posch, Martin, Jaki, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282861/ https://www.ncbi.nlm.nih.gov/pubmed/30088280 http://dx.doi.org/10.1002/sim.7925 |
Ejemplares similares
-
Adaptive designs for subpopulation analysis optimizing utility functions
por: Graf, Alexandra C, et al.
Publicado: (2015) -
Sample Size Reassessment and Hypothesis Testing in Adaptive Survival Trials
por: Magirr, Dominic, et al.
Publicado: (2016) -
A critical review of graphics for subgroup analyses in clinical trials
por: Ballarini, Nicolás M., et al.
Publicado: (2020) -
Optimizing subgroup selection in two‐stage adaptive enrichment and umbrella designs
por: Ballarini, Nicolás M., et al.
Publicado: (2021) -
A multiple comparison procedure for dose‐finding trials with subpopulations
por: Thomas, Marius, et al.
Publicado: (2019)