Cargando…

Correlation of Serum Levels of Urokinase Activation Plasminogen (uPA) and Its Inhibitor (PAI-1) with Hormonal and HER-2 Status in the Early Invasive Breast Cancer

INTRODUCTION: Breast cancer is the most common malignant tumor in women. On the list of causes of death immediately after lung cancer. It is a heterogeneous disease, considering the differences in morphological, cytogenetic, molecular, clinical and therapeutic aspects, so that the prognosis in a pat...

Descripción completa

Detalles Bibliográficos
Autor principal:	Pusina, Sadat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academy of Medical Sciences of Bosnia and Herzegovina 2018
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282918/ https://www.ncbi.nlm.nih.gov/pubmed/30524164 http://dx.doi.org/10.5455/medarh.2018.72.335-340

Ejemplares similares

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas.
por: Bouchet, C., et al.
Publicado: (1994)

Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) in breast cancer - correlation with traditional prognostic factors
por: Lampelj, Maja, et al.
Publicado: (2015)

The autoactivation of human single-chain urokinase-type plasminogen activator (uPA)
por: Torres-Paris, Constanza, et al.
Publicado: (2023)

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer
por: Micalet, Auxtine, et al.
Publicado: (2023)

A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection
por: Sanderson-Smith, Martina L., et al.
Publicado: (2013)

Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation
por: Cunningham, Orla, et al.
Publicado: (2009)

Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer
por: Asuthkar, Swapna, et al.
Publicado: (2013)

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) promote neurorepair in the ischemic brain
por: Merino, Paola, et al.
Publicado: (2017)

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
por: Banys-Paluchowski, Malgorzata, et al.
Publicado: (2019)

Time-varying prognostic impact of tumour biological factors urokinase (uPA), PAI-1 and steroid hormone receptor status in primary breast cancer.
por: Schmitt, M., et al.
Publicado: (1997)

Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA
por: Dreymann, Nico, et al.
Publicado: (2022)

uPA-mediated plasminogen activation is enhanced by polyphosphate
por: Whyte, Claire S., et al.
Publicado: (2020)

Inhibition of urokinase plasminogen activator “uPA” activity alters ethanol consumption and conditioned place preference in mice
por: Al Maamari, Elyazia, et al.
Publicado: (2014)

Expression of uPA, tPA, and PAI-1 in Calcified Aortic Valves
por: Kochtebane, Najlah, et al.
Publicado: (2014)

Prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) in cytosols and pellet extracts derived from 892 breast cancer patients
por: de Witte, J H, et al.
Publicado: (1999)

Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
por: Mahmood, Niaz, et al.
Publicado: (2018)

Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc
por: Kuhn, W, et al.
Publicado: (1999)

A Pilot Study of Urokinase-Type Plasminogen Activator (uPA) Overexpression in the Brush Cytology of Patients with Malignant Pancreatic or Biliary Strictures
por: Gibbs, John F., et al.
Publicado: (2009)

Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK)
por: Santos, Nancy Dos, et al.
Publicado: (2007)

Impact of uPA/PAI-1 and disseminated cytokeratin-positive cells in breast cancer
por: Märkl, Bruno, et al.
Publicado: (2019)

Prognostic significance of uPA/PAI-1 level, HER2 status, and traditional histologic factors for survival in node-negative breast cancer patients
por: Dovnik, Nina Fokter, et al.
Publicado: (2016)

Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients
por: Kotzsch, Matthias, et al.
Publicado: (2011)

Tumor Budding, uPA, and PAI-1 in Colorectal Cancer: Update of a Prospective Study
por: Märkl, Bruno, et al.
Publicado: (2017)

uPA‐PAI‐1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils
por: Uhl, Bernd, et al.
Publicado: (2021)

TEM8 functions as a receptor for uPA and mediates uPA-stimulated EGFR phosphorylation
por: Zhang, Lian-Cheng, et al.
Publicado: (2018)

Increased expression of urokinase type plasminogen activator(u-PA), plasminogen activator inhibitor-1(PAI-1), and collagenases in Caco-2 cells infected by Salmonella typhimurium.
por: Park, C. G., et al.
Publicado: (1997)

External quality assessment of trans-European multicentre antigen determinations (enzyme-linked immunosorbent assay) of urokinase-type plasminogen activator (uPA) and its type 1 inhibitor (PAI-1) in human breast cancer tissue extracts.
por: Sweep, C. G., et al.
Publicado: (1998)

uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies
por: Duffy, Michael J, et al.
Publicado: (2014)

Assessment of Ki67 and uPA/PAI-1 expression in intermediate-risk early stage breast cancers
por: Deluche, Elise, et al.
Publicado: (2017)

Independent validation of stromal uPA in ABCSG-08: Level 1b evidence for the prognostic value of uPA immunohistochemistry
por: Singer, C.F., et al.
Publicado: (2022)

The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity
por: Cochran, Blake J, et al.
Publicado: (2009)

The uPA/uPAR system in astrocytic wound healing
por: Yepes, Manuel
Publicado: (2022)

Construction of a Single Lentiviral Vector Containing Tetracycline-Inducible Alb-uPA for Transduction of uPA Expression in Murine Hepatocytes
por: Bai, Jiasi, et al.
Publicado: (2013)

Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array
por: Völker, Hans-Ullrich, et al.
Publicado: (2018)

Upregulation of P2Y(2)R, Active uPA, and PAI-1 Are Essential Components of Hantavirus Cardiopulmonary Syndrome
por: Bondu, Virginie, et al.
Publicado: (2018)

Accumulation of uPA – PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer
por: Schneider, J, et al.
Publicado: (2003)

Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine
por: Wang, Xuanbin, et al.
Publicado: (2016)

Explication of the roles of prostate health index (PHI) and urokinase plasminogen activator (uPA) as diagnostic and predictor tools for prostate cancer in equivocal PSA range of 4–10 ng/mL
por: Nassir, Anmar M., et al.
Publicado: (2020)

Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK
por: Luo, Jie, et al.
Publicado: (2011)

Seahorse-derived peptide suppresses invasive migration of HT1080 fibrosarcoma cells by competing with intracellular α-enolase for plasminogen binding and inhibiting uPA-mediated activation of plasminogen
por: Kim, Yong-Tae, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_n4tf7q35hs2o2oda1g20kt1171