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Long isoform of VEGF stimulates cell migration of breast cancer by filopodia formation via NRP1/ARHGAP17/Cdc42 regulatory network

VEGF stimulates endothelial cells as a key molecule in angiogenesis. VEGF also works as a multifunction molecule, which targets a variety of cell members in the tumor microenvironment. We aimed to reveal VEGF‐related molecular mechanisms on breast cancer cells. VEGF‐knocked‐out MDA‐MB‐231 cells (231...

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Detalles Bibliográficos
Autores principales: Kiso, Marina, Tanaka, Sunao, Saji, Shigehira, Toi, Masakazu, Sato, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282968/
https://www.ncbi.nlm.nih.gov/pubmed/29971782
http://dx.doi.org/10.1002/ijc.31645