A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides

A ruthenium‐catalysed cross‐olefination of diazo compounds and sulfoxonium ylides is presented. Our reaction design exploits the intrinsic difference in reactivity of diazo compounds and sulfoxonium ylides as both carbene precursors and nucleophiles, which results in a highly selective reaction.

Detalles Bibliográficos
Autores principales: Neuhaus, James D., Bauer, Adriano, Pinto, Alexandre, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283242/
https://www.ncbi.nlm.nih.gov/pubmed/30264529
http://dx.doi.org/10.1002/anie.201809934
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author Neuhaus, James D.
Bauer, Adriano
Pinto, Alexandre
Maulide, Nuno
author_facet Neuhaus, James D.
Bauer, Adriano
Pinto, Alexandre
Maulide, Nuno
author_sort Neuhaus, James D.
collection PubMed
description A ruthenium‐catalysed cross‐olefination of diazo compounds and sulfoxonium ylides is presented. Our reaction design exploits the intrinsic difference in reactivity of diazo compounds and sulfoxonium ylides as both carbene precursors and nucleophiles, which results in a highly selective reaction.
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spelling pubmed-62832422018-12-14 A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides Neuhaus, James D. Bauer, Adriano Pinto, Alexandre Maulide, Nuno Angew Chem Int Ed Engl Communications A ruthenium‐catalysed cross‐olefination of diazo compounds and sulfoxonium ylides is presented. Our reaction design exploits the intrinsic difference in reactivity of diazo compounds and sulfoxonium ylides as both carbene precursors and nucleophiles, which results in a highly selective reaction. John Wiley and Sons Inc. 2018-11-08 2018-12-03 /pmc/articles/PMC6283242/ /pubmed/30264529 http://dx.doi.org/10.1002/anie.201809934 Text en © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Neuhaus, James D.
Bauer, Adriano
Pinto, Alexandre
Maulide, Nuno
A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title_full A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title_fullStr A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title_full_unstemmed A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title_short A Catalytic Cross‐Olefination of Diazo Compounds with Sulfoxonium Ylides
title_sort catalytic cross‐olefination of diazo compounds with sulfoxonium ylides
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283242/
https://www.ncbi.nlm.nih.gov/pubmed/30264529
http://dx.doi.org/10.1002/anie.201809934
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