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Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses
Successful T-dependent humoral responses require the production of antibody-secreting plasmablasts, as well as the formation of germinal centers which eventually form high-affinity B cell memory. The ability of B cells to differentiate into germinal center and plasma cells, as well as the ability to...
Autores principales: | Cooper, Lucy, Hailes, Lauren, Sheikh, Amania, Zaph, Colby, Belz, Gabrielle T., Groom, Joanna R., Good-Jacobson, Kim L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283461/ https://www.ncbi.nlm.nih.gov/pubmed/30521606 http://dx.doi.org/10.1371/journal.pone.0208343 |
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