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A novel approach to stabilize fetal cell-free DNA fraction in maternal blood samples for extended period of time
This study was undertaken to evaluate a novel method for stabilizing and preserving the original proportion of cell-free fetal DNA (cffDNA) in maternal blood for extended periods of time without using crosslinking agents, such as formaldehyde, which compromise DNA integrity and extraction efficiency...
Autores principales: | Fernando, M. Rohan, Jiang, Chao, Krzyzanowski, Gary D., Somer-Shely, Tifany, Ryan, Wayne L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283530/ https://www.ncbi.nlm.nih.gov/pubmed/30521613 http://dx.doi.org/10.1371/journal.pone.0208508 |
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