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Phosphate effect on filipin production and morphological differentiation in Streptomyces filipinensis and the role of the PhoP transcription factor

The biosynthesis of the antifungal filipin in Streptomyces filipinensis is very sensitive to phosphate regulation. Concentrations as low as 2.5 mM block filipin production. This effect is, at least in part, produced by repression of the transcription of most filipin biosynthetic genes. The role of t...

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Detalles Bibliográficos
Autores principales: Barreales, Eva G., Payero, Tamara D., de Pedro, Antonio, Aparicio, Jesús F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283541/
https://www.ncbi.nlm.nih.gov/pubmed/30521601
http://dx.doi.org/10.1371/journal.pone.0208278

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