Cargando…

Study of tau pathology in male rTg4510 mice fed with a curcumin derivative Shiga-Y5

Intracellular inclusions of aggregated tau appear in neurons and glial cells in a range of neurodegenerative diseases known as tauopathies. Inhibition of pathological changes in tau is a therapeutic target for tauopathy. We recently synthesized a novel curcumin derivative, named Shiga-Y5, and showed...

Descripción completa

Detalles Bibliográficos
Autores principales: Yanagisawa, Daijiro, Hamezah, Hamizah Shahirah, Durani, Lina Wati, Taguchi, Hiroyasu, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283544/
https://www.ncbi.nlm.nih.gov/pubmed/30521594
http://dx.doi.org/10.1371/journal.pone.0208440