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Study of tau pathology in male rTg4510 mice fed with a curcumin derivative Shiga-Y5
Intracellular inclusions of aggregated tau appear in neurons and glial cells in a range of neurodegenerative diseases known as tauopathies. Inhibition of pathological changes in tau is a therapeutic target for tauopathy. We recently synthesized a novel curcumin derivative, named Shiga-Y5, and showed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283544/ https://www.ncbi.nlm.nih.gov/pubmed/30521594 http://dx.doi.org/10.1371/journal.pone.0208440 |