Anilinoquinoline based inhibitors of trypanosomatid proliferation

We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum. From this same library of compounds, we now report potent compounds against Trypanosoma brucei brucei (which...

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Detalles Bibliográficos
Autores principales: Ferrins, Lori, Sharma, Amrita, Thomas, Sarah M., Mehta, Naimee, Erath, Jessey, Tanghe, Scott, Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Gillingwater, Kirsten, Pollastri, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283615/
https://www.ncbi.nlm.nih.gov/pubmed/30475800
http://dx.doi.org/10.1371/journal.pntd.0006834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283615/
https://www.ncbi.nlm.nih.gov/pubmed/30475800
http://dx.doi.org/10.1371/journal.pntd.0006834

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