GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of immunoglobulin G (IgG) autoantibodies targeting G protein-coupled receptors (GPCR) in...

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Detalles Bibliográficos
Autores principales: Cabral-Marques, Otavio, Marques, Alexandre, Giil, Lasse Melvær, De Vito, Roberta, Rademacher, Judith, Günther, Jeannine, Lange, Tanja, Humrich, Jens Y., Klapa, Sebastian, Schinke, Susanne, Schimke, Lena F., Marschner, Gabriele, Pitann, Silke, Adler, Sabine, Dechend, Ralf, Müller, Dominik N., Braicu, Ioana, Sehouli, Jalid, Schulze-Forster, Kai, Trippel, Tobias, Scheibenbogen, Carmen, Staff, Annetine, Mertens, Peter R., Löbel, Madlen, Mastroianni, Justin, Plattfaut, Corinna, Gieseler, Frank, Dragun, Duska, Engelhardt, Barbara Elizabeth, Fernandez-Cabezudo, Maria J., Ochs, Hans D., al-Ramadi, Basel K., Lamprecht, Peter, Mueller, Antje, Heidecke, Harald, Riemekasten, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283882/
https://www.ncbi.nlm.nih.gov/pubmed/30523250
http://dx.doi.org/10.1038/s41467-018-07598-9

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