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Influence of correlated antigen presentation on T-cell negative selection in the thymus
The thymus is the primary organ for the generation of naive T cells, a key component of the immune system. Tolerance of T cells to self is achieved primarily in the thymic medulla, where immature T cells (thymocytes) sample self-peptides presented by medullary thymic epithelial cells (mTECs). A suff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283997/ https://www.ncbi.nlm.nih.gov/pubmed/30404905 http://dx.doi.org/10.1098/rsif.2018.0311 |