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Multiple Chemical Sensitivity in Chemical Laboratory Workers

BACKGROUND: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of v...

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Autores principales: Pérez-Crespo, Juan, Lobato-Cañón, Rafael, Solanes-Puchol, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Occupational Safety and Health Research Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284157/
https://www.ncbi.nlm.nih.gov/pubmed/30559998
http://dx.doi.org/10.1016/j.shaw.2018.03.001
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author Pérez-Crespo, Juan
Lobato-Cañón, Rafael
Solanes-Puchol, Ángel
author_facet Pérez-Crespo, Juan
Lobato-Cañón, Rafael
Solanes-Puchol, Ángel
author_sort Pérez-Crespo, Juan
collection PubMed
description BACKGROUND: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. METHODS: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). RESULTS: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. CONCLUSIONS: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.
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spelling pubmed-62841572018-12-17 Multiple Chemical Sensitivity in Chemical Laboratory Workers Pérez-Crespo, Juan Lobato-Cañón, Rafael Solanes-Puchol, Ángel Saf Health Work Original Article BACKGROUND: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. METHODS: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). RESULTS: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. CONCLUSIONS: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time. Occupational Safety and Health Research Institute 2018-12 2018-03-09 /pmc/articles/PMC6284157/ /pubmed/30559998 http://dx.doi.org/10.1016/j.shaw.2018.03.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Pérez-Crespo, Juan
Lobato-Cañón, Rafael
Solanes-Puchol, Ángel
Multiple Chemical Sensitivity in Chemical Laboratory Workers
title Multiple Chemical Sensitivity in Chemical Laboratory Workers
title_full Multiple Chemical Sensitivity in Chemical Laboratory Workers
title_fullStr Multiple Chemical Sensitivity in Chemical Laboratory Workers
title_full_unstemmed Multiple Chemical Sensitivity in Chemical Laboratory Workers
title_short Multiple Chemical Sensitivity in Chemical Laboratory Workers
title_sort multiple chemical sensitivity in chemical laboratory workers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284157/
https://www.ncbi.nlm.nih.gov/pubmed/30559998
http://dx.doi.org/10.1016/j.shaw.2018.03.001
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