S1PR1 predicts patient survival and promotes chemotherapy drug resistance in gastric cancer cells through STAT3 constitutive activation

BACKGROUND: S1PR1-STAT3 inter-regulatory loop was initially suggested to be oncogenic in several cancer cells. However, the clinical relevance of this mechanism in tumor progression, disease prognosis and drug response was not established. METHODS: The correlations between S1PR1 transcription, overa...

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Detalles Bibliográficos
Autores principales: Song, Shiyu, Min, Haiyan, Niu, Mengyuan, Wang, Lei, Wu, Yongzheng, Zhang, Bin, Chen, Xiufang, Liang, Qiao, Wen, Yanting, Wang, Yong, Yi, Long, Wang, Hongwei, Gao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284371/
https://www.ncbi.nlm.nih.gov/pubmed/30316864
http://dx.doi.org/10.1016/j.ebiom.2018.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284371/
https://www.ncbi.nlm.nih.gov/pubmed/30316864
http://dx.doi.org/10.1016/j.ebiom.2018.10.005

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