Cargando…

Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers

Mitochondrial disorders (MDs) are inherited multi‐organ diseases with variable phenotypes. Inclusion body myositis (IBM), a sporadic inflammatory muscle disease, also shows mitochondrial dysfunction. We investigated whether primary and secondary MDs modify metabolism to reveal pathogenic pathways an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buzkova, Jana, Nikkanen, Joni, Ahola, Sofia, Hakonen, Anna H, Sevastianova, Ksenia, Hovinen, Topi, Yki‐Järvinen, Hannele, Pietiläinen, Kirsi H, Lönnqvist, Tuula, Velagapudi, Vidya, Carroll, Christopher J, Suomalainen, Anu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284386/ https://www.ncbi.nlm.nih.gov/pubmed/30373890 http://dx.doi.org/10.15252/emmm.201809091

Ejemplares similares

Modified Atkins diet induces subacute selective ragged‐red‐fiber lysis in mitochondrial myopathy patients
por: Ahola, Sofia, et al.
Publicado: (2016)

Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity
por: Pietiläinen, Kirsi H, et al.
Publicado: (2008)

Acquired Obesity Is Associated with Changes in the Serum Lipidomic Profile Independent of Genetic Effects – A Monozygotic Twin Study
por: Pietiläinen, Kirsi H., et al.
Publicado: (2007)

Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect
por: Ignatenko, Olesia, et al.
Publicado: (2020)

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease
por: Soronen, Jarkko, et al.
Publicado: (2016)

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance
por: Yki-Järvinen, Hannele
Publicado: (2015)

Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients
por: Hovinen, Topi, et al.
Publicado: (2021)

Is There Evidence to Support Use of Premixed or Prandial Insulin Regimens in Insulin-Naive or Previously Insulin-Treated Type 2 Diabetic Patients?
por: Yki-Järvinen, Hannele, et al.
Publicado: (2013)

The quest for the missing links in fatty liver genetics: Deep learning to the rescue!
por: Qadri, Sami, et al.
Publicado: (2022)

Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD—A Systematic Review
por: Petäjä, Elina M., et al.
Publicado: (2016)

Comparison of Dorsocervical With Abdominal Subcutaneous Adipose Tissue in Patients With and Without Antiretroviral Therapy–Associated Lipodystrophy
por: Sevastianova, Ksenia, et al.
Publicado: (2011)

Genetic background of ataxia in children younger than 5 years in Finland
por: Ignatius, Erika, et al.
Publicado: (2020)

A complex genomic locus drives mtDNA replicase POLG expression to its disease‐related nervous system regions
por: Nikkanen, Joni, et al.
Publicado: (2017)

Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes
por: Ignatenko, Olesia, et al.
Publicado: (2022)

Use of Genome-Wide Expression Data to Mine the “Gray Zone” of GWA Studies Leads to Novel Candidate Obesity Genes
por: Naukkarinen, Jussi, et al.
Publicado: (2010)

Association of Lipidome Remodeling in the Adipocyte Membrane with Acquired Obesity in Humans
por: Pietiläinen, Kirsi H., et al.
Publicado: (2011)

Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders
por: Tani, Haruna, et al.
Publicado: (2019)

IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder
por: Kuukasjärvi, Anna, et al.
Publicado: (2021)

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
por: Khan, Nahid A, et al.
Publicado: (2014)

Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver
por: Kotronen, Anna, et al.
Publicado: (2009)

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
por: Jian, Ching, et al.
Publicado: (2020)

In vitro Effects of Bacterial Exposure on Secretion of Zonulin Family Peptides and Their Detection in Human Tissue Samples
por: Jian, Ching, et al.
Publicado: (2022)

Attitudes towards genetic testing and information: does parenthood shape the views?
por: Saastamoinen, Antti, et al.
Publicado: (2020)

Inclusion body myositis--a case report.
por: Park, S. H., et al.
Publicado: (1996)

Detecting dysphagia in inclusion body myositis
por: Cox, F. M., et al.
Publicado: (2009)

The Low Prevalence of Inclusion Body Myositis in an Outpatient Rheumatology Myositis Cohort
por: Edigin, Ehizogie, et al.
Publicado: (2020)

Update in inclusion body myositis
por: Machado, Pedro, et al.
Publicado: (2013)

Genetics in inclusion body myositis
por: Rothwell, Simon, et al.
Publicado: (2017)

Work-Related Exhaustion and Telomere Length: A Population-Based Study
por: Ahola, Kirsi, et al.
Publicado: (2012)

Statin-Induced Myositis with Concomitant Myocarditis
por: Patail, Haris, et al.
Publicado: (2022)

Inclusion Body Myositis Treated with Alemtuzumab
por: Sá, Juliana, et al.
Publicado: (2019)

Better glycaemic control and less hypoglycaemia with insulin glargine 300 U/mL vs glargine 100 U/mL: 1‐year patient‐level meta‐analysis of the EDITION clinical studies in people with type 2 diabetes
por: Ritzel, Robert, et al.
Publicado: (2017)

Prospective randomized controlled trial comparing the efficacy and safety of Roux-en-Y gastric bypass and one-anastomosis gastric bypass (the RYSA trial): trial protocol and interim analysis
por: Saarinen, Tuure, et al.
Publicado: (2019)

External Validation and Evaluation of Adding MRI or Extended Myositis Antibody Panel to the 2017 EULAR/ACR Myositis Classification Criteria
por: Luu, Queenie, et al.
Publicado: (2019)

The Effectiveness of eHealth Interventions for Weight Loss and Weight Loss Maintenance in Adults with Overweight or Obesity: A Systematic Review of Systematic Reviews
por: Kupila, Sakris K. E., et al.
Publicado: (2023)

Development and validation of a weight-loss predictor to assist weight loss management
por: Biehl, Alexander, et al.
Publicado: (2023)

Reply: Comment on alemtuzumab and inclusion body myositis
por: Dalakas, Marinos C., et al.
Publicado: (2010)

Inclusion-Body Myositis Associated with Alzheimer's Disease
por: Levacic, Danijela, et al.
Publicado: (2013)

Inclusion body myositis associated with Sjögren’s syndrome
por: Misterska-Skóra, Maria, et al.
Publicado: (2012)

Proteomic study of sporadic inclusion body myositis
por: Li, Ke, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_j7lr55iiu5bn7jidulh7g5utsl