PARP‐1 regulates DNA repair factor availability

PARP‐1 holds major functions on chromatin, DNA damage repair and transcriptional regulation, both of which are relevant in the context of cancer. Here, unbiased transcriptional profiling revealed the downstream transcriptional profile of PARP‐1 enzymatic activity. Further investigation of the PARP‐1...

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Detalles Bibliográficos
Autores principales: Schiewer, Matthew J, Mandigo, Amy C, Gordon, Nicolas, Huang, Fangjin, Gaur, Sanchaika, de Leeuw, Renée, Zhao, Shuang G, Evans, Joseph, Han, Sumin, Parsons, Theodore, Birbe, Ruth, McCue, Peter, McNair, Christopher, Chand, Saswati N, Cendon‐Florez, Ylenia, Gallagher, Peter, McCann, Jennifer J, Poudel Neupane, Neermala, Shafi, Ayesha A, Dylgjeri, Emanuela, Brand, Lucas J, Visakorpi, Tapio, Raj, Ganesh V, Lallas, Costas D, Trabulsi, Edouard J, Gomella, Leonard G, Dicker, Adam P, Kelly, Wm. Kevin, Leiby, Benjamin E, Knudsen, Beatrice, Feng, Felix Y, Knudsen, Karen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284389/
https://www.ncbi.nlm.nih.gov/pubmed/30467127
http://dx.doi.org/10.15252/emmm.201708816

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