Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum

Molluscum contagiosum (MC) manifests as small, umbilicated papules caused by the molluscum contagiosum virus (MCV). The extent of clinical misdiagnosis of MC is unknown. Combined clinical, histopathological, and virological evaluation of 203 consecutive patients with clinical diagnosis of MC treated...

Descripción completa

Detalles Bibliográficos
Autores principales: Trčko, Katarina, Hošnjak, Lea, Kušar, Blanka, Zorec, Tomaž Mark, Kocjan, Boštjan J, Križmarić, Miljenko, Seme, Katja, Miljković, Jovan, Luzar, Boštjan, Poljak, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284465/
https://www.ncbi.nlm.nih.gov/pubmed/30539041
http://dx.doi.org/10.1093/ofid/ofy298
_version_ 1783379339800215552
author Trčko, Katarina
Hošnjak, Lea
Kušar, Blanka
Zorec, Tomaž Mark
Kocjan, Boštjan J
Križmarić, Miljenko
Seme, Katja
Miljković, Jovan
Luzar, Boštjan
Poljak, Mario
author_facet Trčko, Katarina
Hošnjak, Lea
Kušar, Blanka
Zorec, Tomaž Mark
Kocjan, Boštjan J
Križmarić, Miljenko
Seme, Katja
Miljković, Jovan
Luzar, Boštjan
Poljak, Mario
author_sort Trčko, Katarina
collection PubMed
description Molluscum contagiosum (MC) manifests as small, umbilicated papules caused by the molluscum contagiosum virus (MCV). The extent of clinical misdiagnosis of MC is unknown. Combined clinical, histopathological, and virological evaluation of 203 consecutive patients with clinical diagnosis of MC treated at a university hospital during a 5-year period showed the correct clinical diagnosis in 188 of 203 (92.6%) patients. All 15 clinically misdiagnosed MC lesions were histopathologically and virologically confirmed as either common or anogenital warts caused by different human papillomaviruses. The MCV1/MCV2 subtypes ratio was 1.54:1, and the distribution of MCV subtypes differed across patients’ age and anatomical location of lesions.
format Online
Article
Text
id pubmed-6284465
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-62844652018-12-11 Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum Trčko, Katarina Hošnjak, Lea Kušar, Blanka Zorec, Tomaž Mark Kocjan, Boštjan J Križmarić, Miljenko Seme, Katja Miljković, Jovan Luzar, Boštjan Poljak, Mario Open Forum Infect Dis Brief Report Molluscum contagiosum (MC) manifests as small, umbilicated papules caused by the molluscum contagiosum virus (MCV). The extent of clinical misdiagnosis of MC is unknown. Combined clinical, histopathological, and virological evaluation of 203 consecutive patients with clinical diagnosis of MC treated at a university hospital during a 5-year period showed the correct clinical diagnosis in 188 of 203 (92.6%) patients. All 15 clinically misdiagnosed MC lesions were histopathologically and virologically confirmed as either common or anogenital warts caused by different human papillomaviruses. The MCV1/MCV2 subtypes ratio was 1.54:1, and the distribution of MCV subtypes differed across patients’ age and anatomical location of lesions. Oxford University Press 2018-11-12 /pmc/articles/PMC6284465/ /pubmed/30539041 http://dx.doi.org/10.1093/ofid/ofy298 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Trčko, Katarina
Hošnjak, Lea
Kušar, Blanka
Zorec, Tomaž Mark
Kocjan, Boštjan J
Križmarić, Miljenko
Seme, Katja
Miljković, Jovan
Luzar, Boštjan
Poljak, Mario
Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title_full Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title_fullStr Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title_full_unstemmed Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title_short Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum
title_sort clinical, histopathological, and virological evaluation of 203 patients with a clinical diagnosis of molluscum contagiosum
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284465/
https://www.ncbi.nlm.nih.gov/pubmed/30539041
http://dx.doi.org/10.1093/ofid/ofy298
work_keys_str_mv AT trckokatarina clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT hosnjaklea clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT kusarblanka clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT zorectomazmark clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT kocjanbostjanj clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT krizmaricmiljenko clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT semekatja clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT miljkovicjovan clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT luzarbostjan clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum
AT poljakmario clinicalhistopathologicalandvirologicalevaluationof203patientswithaclinicaldiagnosisofmolluscumcontagiosum

Ejemplares similares