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SGLT2 knockout prevents hyperglycemia and is associated with reduced pancreatic β-cell death in genetically obese mice

Inhibition of the sodium-glucose co-transporter type 2 (SGLT2) has received growing acceptance as a novel, safe and effective means to improve glycemic control in patients with type 2 diabetes. Inhibition of SGLT2 lowers the renal glucose threshold and reduces plasma glucose by promoting glucose exc...

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Detalles Bibliográficos
Autores principales:	Jurczak, Michael J., Saini, Saumya, Ioja, Simona, Costa, Diana K., Udeh, Nnamdi, Zhao, Xiaojian, Whaley, Jean M., Kibbey, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284495/ https://www.ncbi.nlm.nih.gov/pubmed/30118626 http://dx.doi.org/10.1080/19382014.2018.1503027

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