Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine

Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccinatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Hoyoung, Shim, Eun Hyoung, You, Sooseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284502/
https://www.ncbi.nlm.nih.gov/pubmed/29852081
http://dx.doi.org/10.1080/21645515.2018.1482172
_version_ 1783379344966549504
author Lee, Hoyoung
Shim, Eun Hyoung
You, Sooseong
author_facet Lee, Hoyoung
Shim, Eun Hyoung
You, Sooseong
author_sort Lee, Hoyoung
collection PubMed
description Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels.
format Online
Article
Text
id pubmed-6284502
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-62845022018-12-10 Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine Lee, Hoyoung Shim, Eun Hyoung You, Sooseong Hum Vaccin Immunother Commentary Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels. Taylor & Francis 2018-06-28 /pmc/articles/PMC6284502/ /pubmed/29852081 http://dx.doi.org/10.1080/21645515.2018.1482172 Text en © 2018 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Commentary
Lee, Hoyoung
Shim, Eun Hyoung
You, Sooseong
Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title_full Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title_fullStr Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title_full_unstemmed Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title_short Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
title_sort immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284502/
https://www.ncbi.nlm.nih.gov/pubmed/29852081
http://dx.doi.org/10.1080/21645515.2018.1482172
work_keys_str_mv AT leehoyoung immunodominancehierarchyofinfluenzasubtypespecificneutralizingantibodyresponseasahurdletoeffectivenessofpolyvalentvaccine
AT shimeunhyoung immunodominancehierarchyofinfluenzasubtypespecificneutralizingantibodyresponseasahurdletoeffectivenessofpolyvalentvaccine
AT yousooseong immunodominancehierarchyofinfluenzasubtypespecificneutralizingantibodyresponseasahurdletoeffectivenessofpolyvalentvaccine

Ejemplares similares