Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by considerable phenotypic and molecular heterogeneity, but the overall survival of HCC patients remains extremely poor. Thus, novel and efficient alternatives to antitumor agents are urgently needed. Pectolinarigenin, a flavonoid compound...

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Detalles Bibliográficos
Autores principales: Wu, Tianchun, Dong, Xiaogang, Yu, Dongdong, Shen, Zhenhua, Yu, Jinbei, Yan, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284530/
https://www.ncbi.nlm.nih.gov/pubmed/30584322
http://dx.doi.org/10.2147/OTT.S186186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284530/
https://www.ncbi.nlm.nih.gov/pubmed/30584322
http://dx.doi.org/10.2147/OTT.S186186

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